Lois' younger sister, Susan, pays the family a visit and brings with her expensive gifts for the boys, biting remarks for Lois and a cold shoulder for Hal – whom she has never forgiven for dumping her for Lois. Lois and Susan's competitive relationship takes a turn for the worse when Susan gives Malcolm and Reese her prize '65 Mustang convertible. But when Lois discovers that Susan needs a kidney transplant, she puts her anger aside and offers to donate her kidney to Susan, which Susan only sees as the perfect opportunity for Lois to one-up her.false2026-04-16 09:48:12Lois's SisterGary MurphyGary Murphy7.42004tt064036013027222ComedyFamily/media/Series/Malcolm In The Middle.2000.INTEGRALE.MULTI.1080p.WEB.x264-FTMVHD/Malcolm In The Middle.S05.MULTI.1080p.WEB.x264-FTMVHD/Malcolm In The Middle.S05E13.MULTI.1080p.WEB.x264-FTMVHD-thumb.jpgFrankie MunizMalcolmActor0/config/metadata/People/F/Frankie Muniz/folder.jpgJane KaczmarekLoisActor1/config/metadata/People/J/Jane Kaczmarek/folder.jpgBryan CranstonHalActor2/config/metadata/People/B/Bryan Cranston/folder.jpgJustin BerfieldReeseActor3/config/metadata/People/J/Justin Berfield/folder.jpgErik Per SullivanDeweyActor4/config/metadata/People/E/Erik Per Sullivan/folder.jpgChristopher MastersonFrancisActor5/config/metadata/People/C/Christopher Masterson/folder.jpgLaurie MetcalfSusanGuestStar1237/config/metadata/People/L/Laurie Metcalf/folder.jpgAbigail MavityMeaganGuestStar1238/config/metadata/People/A/Abigail Mavity/folder.jpgKevin CooneyDr. DumontGuestStar1239/config/metadata/People/K/Kevin Cooney/folder.jpgLyndsy FonsecaOliviaGuestStar1240/config/metadata/People/L/Lyndsy Fonseca/folder.jpgHeather McPhaulTrishGuestStar1241/config/metadata/People/H/Heather McPhaul/folder.jpgJasmine Di AngeloBrittanyGuestStar1242/config/metadata/People/J/Jasmine Di Angelo/folder.jpgKate MinerKatieGuestStar1243/config/metadata/People/K/Kate Miner/folder.jpgJosh JacobsonMattGuestStar1244/config/metadata/People/J/Josh Jacobson/folder.jpgTianna Danielle KenneyButtercup #2GuestStar1245Hayley ErinButtercup #1GuestStar1246/config/metadata/People/H/Hayley Erin/folder.jpgAlyssa MonkaButtercup #3GuestStar1247Montana TsaiButtercup #4GuestStar1248Gracie MarklandButtercup #5GuestStar1249Chanel GainesButtercup #6GuestStar1250Barbara ScolaroButtercup #7GuestStar1565/config/metadata/People/B/Barbara Scolaro/folder.jpgMalcolm in the Middle1352004-02-22subripsubrip00engprogressiveFalseFalsesubripsubrip00fraprogressiveFalseFalsesubripsubrip00fraprogressiveTrueTrue